In this book importance of Asymmetric Synthesis are given with examples. It has underlined concepts developed starting with basic principles of stereochemistry. It is based on drug required, four methodologies are given. The text is written in a simple and lucid style. The topics have been dealt with systematically, diagrammatically and in a lucid language. The book is based on three important principles. First, concepts and terminology used in asymmetric synthesis, second, the four types of asymmetric synthesis and third, applications of asymmetric synthesis. Students, teachers and researchers need to understand the methodology of asymmetric synthesis, because of the crucial role this plays in the organic synthesis, especially in synthesis of drugs. An understanding of different methods of asymmetric synthesis is essential for the planning of drug synthesis using the knowledge of QSAR.